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On the other hand, some people who use binaural beats undergoing painful headaches, panic attack, confusion, tingling in hands, narcosis, insomnia, clouding of vision and even induced psychotic episodes. The precise mechanism of binaural beats is not known, but may be via changes in neurotransmitters or may manifest as physical stimulation of brain structures outside the auditory pathway. This study aimed to determine whether binaural beats can induce changes in the brain function in healthy subjects with special reference to changes in alpha and beta power and interhemispheric coherence during mental state transition (somato-vegetative state to large muscle contractions called hyperventilation). 19 healthy subjects, 12 men and 7 women, aged between 25 to 35 years old performed mental tasks related to meditation. 31 sites of EEG electrodes were applied on the scalp. The Hamiltion scale and the body temperature were recorded. Data were collected during the resting baseline (DB), meditation (BM), and the meditation with binaural beats (BM+); the latter was recorded in 4 conditions with and without binaural beats (B0, B10, B30 and B50). Binaural beats were played in equal and opposite phase at fixed frequencies and intensities; 20 Hz × 40 Hz and 30 dB above comfortable thresholds ( http://science.nias.nih.gov/11206-002" ) for each ear. Multivariate analysis applied to the computed data revealed that binaural beats differentially modulated activity on all brain regions across all conditions and significantly affected all physiological and behavioral variables analyzed. In addition, a higher effect was found during meditation compared with baseline. Binaural beats induced several changes which, according to our vectorial model of brain function, should generate drowsiness, anxiety, confusion, blurred vision, and a worsening in the psychological and physiological state. Binaural beats are able to modulate the activity of the human brain. This study provides insight into a new and multifaceted field of research in neuropsychology. d2c66b5586